Sculptra Aesthetic is more effective than Cosmoplast human-derived collagen and lasts as long as 25 months, according to a study published in the Journal of the American Academy of Dermatology.

233 patients were treated randomly with Cosmoplast or Sculptra Aesthetic at 3-week intervals. Injections were performed to reduce the appearance of the nasolabial folds – the lines that travel from the nose to the corner of the mouth. Post treatment visits were conducted at 3 weeks, 3 months, 6 months, 9 months and 13 months after the final injection.

Highlights of the study:

  • During post-operative evaluations, Sculptra scored much higher on the wrinkle assessment scale.
  • When the patients treated with Sculptra were followed an additional 12 months, they exhibited results lasting over two years.
  • Results had a very natural appearance. “[Sculptra] works gradually to replace lost collagen due to aging, resulting in a more natural-looking appearance” said Dr. Gary Monheit of the University of Alabama Medical Center.
  • Side effects were mild or moderate in intensity and overall, they occurred more frequently in the collagen group.