Evolence
Evolence is a collagen-based dermal filler made by OrthoNeutrogena and FDA approved for the correction of moderate to severe facial wrinkles and folds. More and more physicians have been using Evolence for its smooth natural results and reduced side effects.
The composition of Evolence is nothing less than state-of-the-art. Made of purified porcine collagen that has been stabilized and cross-linked with ribose, the composition is strikingly similar to human collagen, so it provides natural results. Because Evolence is biocompatible, treatment requires no allergy test, so you can come in and get treated in one quick visit.
The best candidates for Evolence will exhibit facial wrinkles and folds such as “smile lines” or “marionette lines.” During treatment, Dr. Mandell-Brown injects Evolence into the targeted area using a fine needle and slightly massages it into place to ensure a smooth result. The improvements will be visible immediately and residual bruising will be minimal, if it occurs at all. You can expect the results of Evolence to be apparent for 6 months to a year.
If you need more information, have questions or concerns, or if you want to schedule a treatment, contact the Cincinnati cosmetic surgery office of Dr. Mark Mandell-Brown.



